Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 5/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749973 | 0.83 | LTA4H (0.68) | LTA4HPLA2G2ATRPM8BRD4MAPT | |
| SCHEMBL8303606 | 0.79 | LTA4H (0.46) | LTA4HPLA2G2ATRPM8BRD4L3MBTL1 | |
| SCHEMBL27527029 | 0.79 | LTA4H (0.46) | LTA4HPLA2G2ATRPM8BRD4ELANE | |
| SCHEMBL3621324 | 0.79 | LTA4H (0.46) | LTA4HPLA2G2ATRPM8BRD4ELANE | |
| SCHEMBL9749866 | 0.78 | LTA4H (0.46) | LTA4HPLA2G2ATRPM8BRD4ELANE | |
| SCHEMBL8304176 | 0.76 | L3MBTL1 (0.48) | LTA4HPLA2G2ATRPM8BRD4ELANE | |
| SCHEMBL23887763 | 0.75 | LTA4H (0.54) | LTA4HPLA2G2ATRPM8BRD4ELANE | |
| SCHEMBL27189563 | 0.75 | TRPM8 (0.45) | LTA4HPLA2G2ATRPM8BRD4ELANE | |
| SCHEMBL5479712 | 0.75 | TRPM8 (0.76) | LTA4HPLA2G2ATRPM8ADRB3L3MBTL1 | |
| SCHEMBL8307738 | 0.75 | BRD4 (0.48) | BRD4L3MBTL1MAPTSMN1; SMN2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469833-B1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY CO ELI (GB) | 1999-09-08 | — | — | EP | disclosed |
| US-5281593-A | Pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0469833-A1 | N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them | LILLY INDUSTRIES LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |