Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.32 |
| ▸ | HPGD | P15428 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 4/20 | 0.31 |
| ▸ | CASP7 | P55210 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307946 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNACRHR1PTGS2 | |
| SCHEMBL8303146 | 0.83 | CRHR1 (0.31) | CRHR1 | |
| SCHEMBL4442406 | 0.83 | SIRT2 (0.38) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL4563793 | 0.82 | SIRT2 (0.35) | ALDH1A1SMN1; SMN2LMNAMAPTCRHR1 | |
| SCHEMBL7514117 | 0.81 | SIRT2 (0.34) | ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4442084 | 0.81 | SIRT2 (0.34) | ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL8305905 | 0.81 | RXRA (0.45) | ALDH1A1HPGDKDM4EMAPTTSHR | |
| SCHEMBL7514067 | 0.81 | MAPT (0.36) | ALDH1A1HPGDKDM4EGAAALOX15 | |
| SCHEMBL8303347 | 0.81 | NR4A2 (0.35) | ALDH1A1KDM4ELMNAMAPTHSD17B10 | |
| SCHEMBL8303845 | 0.80 | RXRA (0.41) | ALDH1A1HPGDKDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036882-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |