SCHEMBL8304698

SCHEMBL8304698

Cc1cc[c]c(C(F)(F)F)n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.36
RAB9A P51151 1/20 0.36
CCR5 P51681 1/20 0.36
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
CYP1A2 P05177 2/20 0.31
CCR8 P51685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120639 0.76 TRPV4 (0.31)
SCHEMBL790134 0.74 CYP3A4 (0.30)
SCHEMBL21855912 0.74 BACE1 (0.36)
SCHEMBL491269 0.74 NFE2L2 (0.34) CYP1A2
SCHEMBL8678834 0.71 SDHB (0.33) RAB9A
SCHEMBL1949175 0.70
SCHEMBL324327 0.69
SCHEMBL155557 0.67 TRPV3 (0.32)
SCHEMBL22394299 0.67 KIF11 (0.42) RAB9A
SCHEMBL789708 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576251-B1 Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment SUNTORY LTD (JP) 1999-11-24 EP disclosed
US-5424310-A Substituted 1,2,4-triazine-3,5-dione derivative and anticoccidial drug composition containing the same as active component SUNTORY LIMITED (JP) 1995-06-13 US disclosed
EP-0576251-A1 Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment SUNTORY LIMITED (JP) 1993-12-29 EP disclosed