Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 5/20 | 0.57 |
| ▸ | PTGES | O14684 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508983 | 0.95 | CTRC (0.56) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL27269693 | 0.94 | CTRC (0.58) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL22497686 | 0.94 | CTRC (0.58) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL1358807 | 0.94 | CTRC (0.58) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL1358810 | 0.94 | CTRC (0.58) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL3861924 | 0.90 | PPARG (0.68) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL29119310 | 0.88 | PPARA (0.58) | PPARGPPARAPTGESALOX5ALDH1A1 | |
| SCHEMBL6382529 | 0.88 | CTRC (0.46) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL27303106 | 0.88 | PPARG (0.46) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL7763599 | 0.88 | ALDH1A1 (0.48) | PPARGPPARAPTGESALOX5CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216798-A2 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2017-09-13 | — | — | EP | disclosed |
| EP-2673285-B1 | KETOLIDE COMPOUNDS | WOCKHARDT LTD (IN) | 2017-07-19 | — | — | EP | disclosed |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| US-9175031-B2 | Ketolide compounds | WOCKHARDT LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |
| US-RE45548-E1 | Functionalized drugs and polymers derived therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-8846845-B2 | Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices | BEZWADA BIOMEDICAL, LLC (US) | 2014-09-30 | — | — | US | disclosed |
| US-20140005133-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2014-01-02 | — | — | US | disclosed |
| EP-2673285-A1 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2013-12-18 | — | — | EP | disclosed |
| EP-2298235-B1 | Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices | BEZWADA BIOMEDICAL LLC (US) | 2013-11-06 | — | — | EP | disclosed |
| US-8409559-B2 | Functionalized drugs and polymers derived therefrom | Bezwada Biomedical, Inc. (US) | 2013-04-02 | — | — | US | disclosed |
| US-7772352-B2 | Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices | BEZWADA BIOMEDICAL LLC (US) | 2010-08-10 | — | — | US | disclosed |
| US-20100152272-A1 | FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2010-06-17 | — | — | US | disclosed |
| US-7691364-B2 | Functionalized drugs and polymers derived therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2010-04-06 | — | — | US | disclosed |
| EP-1937182-A4 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | BEZWADA BIOMEDICAL LLC (US) | 2009-07-15 | — | — | EP | disclosed |
| EP-1937182-A2 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | Bezwada Biomedical LLC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1931334-A2 | FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM | Bezwada Biomedical LLC (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007030538-A2 | FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007030464-A2 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | BEZWADA BIOMEDICAL LLC (US) | 2007-03-15 | — | — | WO | disclosed |
| US-20060188547-A1 | Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices | BEZWADA BIOMEDICAL, LLC (US) | 2006-08-24 | — | — | US | disclosed |
| US-20060172983-A1 | Functionalized drugs and polymers derived therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152272-A1 | FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM | OGFR, LOX, DDO | PPARG 3094/4885PPARA 3419/4885PTGES 1341/4885 |
| US-20060172983-A1 | Functionalized drugs and polymers derived therefrom | OGFR, LOX, OPRM1 | PPARG 2602/4885PPARA 3102/4885PTGES 1674/4885 |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | AKR1C3, AKR1D1, AKR1C1 | PPARG 1365/4885PPARA 1526/4885PTGES 1327/4885 |
| US-20140005133-A1 | KETOLIDE COMPOUNDS | AKR1C3, AKR1D1, AKR1C1 | PPARG 1333/4885PPARA 1538/4885PTGES 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.