Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298757 | 0.87 | HRH3 (0.49) | FFAR4HRH3 | |
| SCHEMBL8298648 | 0.74 | CDK9 (0.36) | FFAR4HRH3CCNT1CDK9 | |
| SCHEMBL8305658 | 0.74 | CCNT1 (0.38) | FFAR4CCNT1CDK9 | |
| SCHEMBL8305336 | 0.72 | KDM4E (0.43) | FFAR4HRH3CCNT1CDK9 | |
| SCHEMBL8305139 | 0.71 | CDK9 (0.36) | FFAR4HRH3CCNT1CDK9 | |
| SCHEMBL22446347 | 0.70 | BTK (0.45) | — | |
| SCHEMBL16499811 | 0.70 | HTR2A (0.44) | FFAR4 | |
| SCHEMBL8304380 | 0.69 | DRD3 (0.36) | CCNT1CDK9 | |
| SCHEMBL8613755 | 0.68 | ITGB3 (0.56) | FFAR4HRH3 | |
| SCHEMBL8301327 | 0.68 | KDM4E (0.43) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |