Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12278263 | 0.81 | KDM4E (0.41) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL8308192 | 0.76 | KMT2A (0.58) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL8310965 | 0.74 | LMNA (0.50) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8308971 | 0.74 | MAPT (0.43) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12279050 | 0.72 | NR4A2 (0.38) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12278761 | 0.70 | MAOA (0.41) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12278045 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18000203 | 0.70 | GPR3 (0.41) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9198888 | 0.68 | KDM4E (0.46) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL29955794 | 0.68 | GPR3 (0.36) | MEN1KMT2AKDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650599-B1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS ISLE OF MAN LIMITED (GB) | 1999-11-03 | — | — | EP | disclosed |
| US-5726063-A | Method of colorimetric analysis of malonic dialdehyde and 4-hydroxy-2-enaldehydes as indexes of lipid peroxidation, kits for carrying out said method, substituted indoles for use in said method and their preparation | OXIS ISLE OF MAN, LIMITED (US) | 1998-03-10 | — | — | US | disclosed |