Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10103705 | 0.80 | KMT2A (0.76) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8308971 | 0.80 | MAPT (0.43) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8310965 | 0.80 | LMNA (0.50) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8305086 | 0.80 | BRPF1 (0.46) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28673739 | 0.79 | ALDH1A1 (0.47) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL30419565 | 0.79 | ALDH1A1 (0.47) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL30419560 | 0.79 | MAOB (0.52) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28650953 | 0.79 | MAOB (0.52) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL12278263 | 0.77 | KDM4E (0.41) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL12278045 | 0.76 | KDM4E (0.40) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997329-B | Polysubstituted 3- (3-benzo [ b ] selenophenyl) -1H-2-aryl indole and derivative and synthesis method thereof | 湘潭大学 | 2021-06-04 | — | — | CN | claimed |
| CN-108997329-A | Polysubstituted 3-(3- benzo [b] selenophen base) -1H-2- (hetero) aryl indole and derivative and its synthetic method | 湘潭大学 | 2018-12-14 | — | — | CN | claimed |
| CN-108997329-B | Polysubstituted 3- (3-benzo [ b ] selenophenyl) -1H-2-aryl indole and derivative and synthesis method thereof | 湘潭大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-108997329-A | Polysubstituted 3-(3- benzo [b] selenophen base) -1H-2- (hetero) aryl indole and derivative and its synthetic method | 湘潭大学 | 2018-12-14 | — | — | CN | disclosed |
| EP-0650599-B1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS ISLE OF MAN LIMITED (GB) | 1999-11-03 | — | — | EP | disclosed |
| US-5726063-A | Method of colorimetric analysis of malonic dialdehyde and 4-hydroxy-2-enaldehydes as indexes of lipid peroxidation, kits for carrying out said method, substituted indoles for use in said method and their preparation | OXIS ISLE OF MAN, LIMITED (US) | 1998-03-10 | — | — | US | disclosed |
| US-RE29834-E | PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-3959310-A | BENZINDOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |