Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306006 | 0.77 | LTA4H (0.44) | MAPTSMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL19602284 | 0.75 | ACHE (0.52) | GCKMAPTPOLBHSP90AA1ALDH1A1 | |
| SCHEMBL19602281 | 0.68 | MAPT (0.72) | GCKMAPTPOLBHSP90AA1ALDH1A1 | |
| SCHEMBL19602282 | 0.68 | POLB (0.43) | GCKMAPTPOLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL778774 | 0.68 | MAOB (0.44) | MAPTPOLBHSP90AA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL328383 | 0.68 | ACHE (0.52) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21486338 | 0.67 | TEAD4 (0.45) | GCKMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL29062557 | 0.67 | SMN1; SMN2 (0.50) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28400248 | 0.66 | NFE2L2 (0.39) | MAPTPOLBHSP90AA1ALDH1A1HTR1A | |
| SCHEMBL257605 | 0.66 | ACHE (0.47) | MAPTPOLBHSP90AA1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937051-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1998020003-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-14 | — | — | WO | claimed |
| EP-0937051-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020003-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |