Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 9/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | BCL3 | P20749 | 1/20 | 0.34 |
| ▸ | HCN1 | O60741 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305625 | 0.90 | GAA (0.40) | BCL3 | |
| SCHEMBL8299902 | 0.86 | ABL1 (0.38) | WNT3AABL1KCNH2 | |
| SCHEMBL8302364 | 0.85 | HIF1A (0.47) | — | |
| SCHEMBL8305595 | 0.84 | PARP1 (0.34) | KCNH2BCL3 | |
| SCHEMBL8300908 | 0.83 | MAPT (0.36) | — | |
| SCHEMBL8306105 | 0.81 | PKM (0.40) | KCNH2BCL3 | |
| SCHEMBL1646552 | 0.80 | AURKA (0.46) | RXFP1WNT3AABL1KCNH2ACKR3 | |
| SCHEMBL8299878 | 0.79 | NPC1 (0.42) | ABL1 | |
| SCHEMBL8302374 | 0.78 | KDM4E (0.34) | CNR2 | |
| SCHEMBL14311682 | 0.78 | AURKA (0.43) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005002552-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASES INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-01-13 | — | — | WO | disclosed |