Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306272 | 0.93 | SMO (0.38) | CARM1PRMT6 | |
| SCHEMBL8310235 | 0.90 | GRIN2B (0.49) | GRIN2BDRD3DRD2DRD4SLC6A5 | |
| SCHEMBL8306217 | 0.83 | SMO (0.40) | — | |
| SCHEMBL8309546 | 0.82 | FYN (0.47) | GRIN2BDRD2 | |
| SCHEMBL8309952 | 0.82 | SMO (0.38) | CARM1PRMT6 | |
| SCHEMBL8188026 | 0.79 | GRIN2B (0.41) | GRIN2BADRB3CARM1PRMT6SLC6A5 | |
| SCHEMBL8309596 | 0.78 | SMO (0.38) | — | |
| SCHEMBL8309243 | 0.78 | MTTP (0.45) | — | |
| SCHEMBL8306747 | 0.77 | KDM4E (0.36) | GRIN2B | |
| SCHEMBL8309882 | 0.75 | DRD2 (0.46) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759027-B1 | BICYCLIC AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHETASE | ASTRA AB (SE) | 1999-08-04 | — | — | EP | claimed |