Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308653 | 0.87 | RIPK1 (0.34) | KDM4ESMN1; SMN2HPGDCNR1CNR2 | |
| SCHEMBL8308129 | 0.82 | — | — | |
| SCHEMBL8957108 | 0.76 | DPP4 (0.34) | KDM4ESMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL8304861 | 0.73 | MEN1 (0.31) | HTTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL2696901 | 0.72 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL8986742 | 0.71 | HIF1A (0.31) | HSD17B10 | |
| SCHEMBL933947 | 0.69 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL21645459 | 0.68 | PLK1 (0.39) | KDM4ESMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL8957126 | 0.65 | NPC1 (0.42) | KDM4EHSD17B10ALDH1A1LMNAMAPT | |
| SCHEMBL158855 | 0.65 | POLB (0.40) | KDM4ESMN1; SMN2HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638074-B1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0638074-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF Aktiengesellschaft (DE) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993022295-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |