Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306215 | 0.89 | EPHX2 (0.45) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8309192 | 0.84 | CYP3A4 (0.39) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8306914 | 0.71 | CYP1B1 (0.43) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8306264 | 0.71 | CYP1B1 (0.63) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8304422 | 0.71 | CYP1B1 (0.63) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8575611 | 0.71 | QPCT (0.45) | CYP3A4MEN1KMT2AMAPTMAOB | |
| SCHEMBL8304396 | 0.70 | MAOB (0.59) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8305061 | 0.70 | CYP1B1 (0.59) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8306988 | 0.70 | CYP1B1 (0.42) | CYP3A4MEN1KMT2AUSP2LMNA | |
| SCHEMBL8304673 | 0.68 | BRD4 (0.40) | CYP3A4MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |