Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306527 | 0.84 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL8269433 | 0.78 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL833047 | 0.78 | CD44 (0.42) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL8292367 | 0.73 | NNMT (0.37) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL8291075 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL14490504 | 0.73 | L3MBTL1 (0.42) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL377405 | 0.69 | MAPT (0.53) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL29871026 | 0.64 | KDM4E (0.39) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL28629137 | 0.64 | KDM4E (0.39) | KDM4EALDH1A1MAPTHSD17B10TLR4 | |
| SCHEMBL11704181 | 0.64 | MAPT (0.57) | KDM4EALDH1A1MAPTHSD17B10TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |