Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6100506 | 0.93 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6099481 | 0.79 | ALDH1A1 (0.40) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6099648 | 0.77 | ALDH1A1 (0.45) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6097459 | 0.74 | S100A4 (0.47) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL8309976 | 0.73 | POLB (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Water SCHEMBL6101423 | 0.73 | S100A4 (0.46) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6099876 | 0.71 | LMNA (0.40) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6106397 | 0.71 | ALDH1A1 (0.51) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL12702171 | 0.68 | ALDH1A1 (0.32) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6100934 | 0.68 | S100A4 (0.34) | MAPTMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912565-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997048704-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |