Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420496 | 0.79 | CYP19A1 (1.00) | CYP19A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL8310965 | 0.76 | LMNA (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8305086 | 0.76 | BRPF1 (0.46) | MAPTNPC1RAB9AKMT2ACYP1A2 | |
| SCHEMBL8308192 | 0.75 | KMT2A (0.58) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL17199054 | 0.74 | CYP19A1 (0.75) | CYP19A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL17199051 | 0.74 | CYP19A1 (0.75) | CYP19A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL23320529 | 0.74 | CYP19A1 (0.74) | CYP19A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL30943221 | 0.74 | CYP19A1 (0.66) | CYP19A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL30943232 | 0.74 | CYP19A1 (0.74) | CYP19A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL23320535 | 0.74 | CYP19A1 (0.66) | CYP19A1MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650599-B1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS ISLE OF MAN LIMITED (GB) | 1999-11-03 | — | — | EP | disclosed |
| US-5726063-A | Method of colorimetric analysis of malonic dialdehyde and 4-hydroxy-2-enaldehydes as indexes of lipid peroxidation, kits for carrying out said method, substituted indoles for use in said method and their preparation | OXIS ISLE OF MAN, LIMITED (US) | 1998-03-10 | — | — | US | disclosed |