Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308838 | 0.89 | DRD4 (0.38) | GPR55CNR1CNR2DRD4IRAK4 | |
| SCHEMBL7799610 | 0.88 | HTR4 (0.38) | GPR55KMT2AHTT | |
| Hydrochloric Acid SCHEMBL7943941 | 0.87 | HTR4 (0.37) | GPR55KMT2AHTT | |
| SCHEMBL8305942 | 0.87 | TP53 (0.40) | GPR55CNR1KMT2ACNR2 | |
| SCHEMBL8310238 | 0.87 | DRD4 (0.48) | KMT2ADRD4ALPL | |
| SCHEMBL6967209 | 0.86 | DRD4 (0.37) | KMT2ADRD4 | |
| SCHEMBL7799616 | 0.85 | HTR4 (0.36) | GPR55CNR1KMT2ADRD4SMN1; SMN2 | |
| SCHEMBL6958303 | 0.85 | DRD4 (0.41) | GPR55CNR1DRD4 | |
| SCHEMBL8305104 | 0.82 | HTR4 (0.44) | GPR55CNR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8368070 | 0.82 | HTR4 (0.43) | GPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |
| EP-0591027-A1 | Piperidine derivatives, their preparation and their use as medicine | SYNTHELABO (FR) | 1994-04-06 | — | — | EP | disclosed |