Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 8/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307501 | 0.87 | GPR55 (0.39) | GPR55KMT2ACNR1CNR2 | |
| SCHEMBL8308257 | 0.81 | NR3C1 (0.39) | TP53GPR55NR3C1CNR1NPBWR1 | |
| SCHEMBL7799610 | 0.81 | HTR4 (0.38) | GPR55MEN1ALDH1A1KMT2A | |
| SCHEMBL8517107 | 0.81 | TP53 (0.41) | TP53GPR55SUV39H2CNR1 | |
| SCHEMBL7799616 | 0.80 | HTR4 (0.36) | GPR55MEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL6967209 | 0.79 | DRD4 (0.37) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7749150 | 0.77 | MDM2 (0.37) | TP53GPR55NR3C1CNR1MAPT | |
| SCHEMBL6962731 | 0.77 | MDM2 (0.37) | TP53GPR55NR3C1CNR1MAPT | |
| SCHEMBL8303784 | 0.72 | NR3C1 (0.39) | TP53GPR55NR3C1CNR1 | |
| SCHEMBL8368044 | 0.70 | KEAP1 (0.40) | TP53GPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |