Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | PAICS | P22234 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958303 | 0.95 | DRD4 (0.41) | DRD4PAICSALDH1A1GPR55CNR1 | |
| SCHEMBL8307501 | 0.89 | GPR55 (0.39) | DRD4GPR55CNR1IRAK4CNR2 | |
| SCHEMBL7799616 | 0.87 | HTR4 (0.36) | DRD4ALDH1A1GPR55CNR1HTR4 | |
| SCHEMBL7799610 | 0.86 | HTR4 (0.38) | ALDH1A1GPR55HTR4STAT3HPGD | |
| SCHEMBL8368080 | 0.86 | FAAH (0.43) | DRD4ALDH1A1CNR1 | |
| Hydrochloric Acid SCHEMBL7943941 | 0.85 | HTR4 (0.37) | GPR55HTR4TDP1 | |
| SCHEMBL8305942 | 0.85 | TP53 (0.40) | ALDH1A1GPR55CNR1SUV39H2CNR2 | |
| SCHEMBL8304880 | 0.82 | HTR4 (0.44) | HTR4SUV39H2 | |
| Bromide SCHEMBL8366387 | 0.82 | HTR4 (0.43) | HTR4SUV39H2 | |
| SCHEMBL8310238 | 0.82 | DRD4 (0.48) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |