SCHEMBL8307671

SCHEMBL8307671

CN(C)C1CCN(C(=O)CCCN2CCC(n3nc(-c4cc(Cl)cc5c4OCCC5)oc3=O)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.35
GPR55 Q9Y2T6 4/20 0.34
MCHR1 Q99705 4/20 0.34
HTR4 Q13639 3/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8308652 0.98 CNR1 (0.34) CNR1GPR55MCHR1HTR4CNR2
SCHEMBL8304883 0.79 HTR4 (0.35) HTR4
SCHEMBL6961974 0.79 HTR4 (0.42) CNR1HTR4
SCHEMBL8305677 0.76 HTR4 (0.43) CNR1GPR55HTR4CNR2
Hydrochloric Acid SCHEMBL8366413 0.75 HTR4 (0.43) CNR1GPR55HTR4CNR2
SCHEMBL8304451 0.73 NOTUM (0.38) CNR1GPR55HTR4
Hydrochloric Acid SCHEMBL8366408 0.73 NOTUM (0.37) CNR1GPR55HTR4
SCHEMBL7804900 0.72 BRD4 (0.33)
SCHEMBL8303784 0.72 NR3C1 (0.39) CNR1GPR55HTR4
SCHEMBL8305672 0.72 DRD2 (0.44) CNR1GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863897-B1 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS SYNTHELABO (FR) 1999-06-16 EP disclosed