Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 6/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307671 | 0.98 | CNR1 (0.35) | CNR1GPR55HTR4MCHR1CNR2 | |
| SCHEMBL6961974 | 0.81 | HTR4 (0.42) | CNR1HTR4 | |
| SCHEMBL8304883 | 0.78 | HTR4 (0.35) | HTR4 | |
| SCHEMBL8305677 | 0.75 | HTR4 (0.43) | CNR1GPR55HTR4CNR2 | |
| SCHEMBL8304451 | 0.73 | NOTUM (0.38) | CNR1GPR55HTR4 | |
| Hydrochloric Acid SCHEMBL8366408 | 0.72 | NOTUM (0.37) | CNR1GPR55HTR4 | |
| SCHEMBL8305672 | 0.72 | DRD2 (0.44) | CNR1GPR55 | |
| SCHEMBL7804900 | 0.72 | BRD4 (0.33) | — | |
| SCHEMBL8303784 | 0.72 | NR3C1 (0.39) | CNR1GPR55HTR4 | |
| SCHEMBL8304833 | 0.71 | GPR55 (0.39) | CNR1GPR55HTR4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |