Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.37 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304573 | 0.80 | HTR3A (0.35) | GPR55CNR1 | |
| SCHEMBL8308257 | 0.80 | NR3C1 (0.39) | NR3C1GPR119GPR55CNR1HTR4 | |
| SCHEMBL6962731 | 0.76 | MDM2 (0.37) | NR3C1GPR55CNR1HTR4PIK3CD | |
| SCHEMBL7749150 | 0.76 | MDM2 (0.37) | NR3C1GPR55CNR1HTR4PIK3CD | |
| SCHEMBL7808385 | 0.75 | HTR3A (0.34) | GPR55 | |
| Hydrochloric Acid SCHEMBL7945320 | 0.74 | HTR3A (0.34) | GPR55 | |
| Hydrochloric Acid SCHEMBL8366408 | 0.74 | NOTUM (0.37) | GPR55CNR1HTR4 | |
| SCHEMBL8304833 | 0.74 | GPR55 (0.39) | GPR55CNR1HTR4 | |
| Hydrochloric Acid SCHEMBL8369921 | 0.73 | DRD2 (0.45) | GPR55CNR1 | |
| Hydrochloric Acid SCHEMBL8366400 | 0.73 | GPR55 (0.39) | GPR55CNR1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929089-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |