SCHEMBL83079

SCHEMBL83079

O=C1C=CC(=O)N1SSN1C(=O)C=CC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 0.42
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
FAAH O00519 7/20 0.38
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
GMNN O75496 1/20 0.36
THPO P40225 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
HSP90AA1 P07900 3/20 0.35
TLR9 Q9NR96 2/20 0.35
PKM P14618 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
XBP1 P17861 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709406 0.79 MGLL (0.42) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL4340966 0.73
SCHEMBL24003668 0.73
SCHEMBL16256331 0.73
SCHEMBL5577325 0.71 MGLL (0.43) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL19954787 0.69 MGLL (0.35) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL22407268 0.68 MGLL (0.46) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL19057261 0.67 MGLL (0.46) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL19848642 0.67 MGLL (0.39) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL11749637 0.67 ALDH1A1 (0.47) MGLLGSK3AGSK3BFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118755466-B Pressure production integrated emulsion type fracturing fluid 陕西万德石油科技有限公司 2024-12-20 CN claimed
CN-118755466-A Pressure production integrated emulsion type fracturing fluid 陕西万德石油科技有限公司 2024-10-11 CN claimed
CN-118599107-A High-strength, high-toughness, high-heat-resistance and detachable thermosetting polymer based on dithiobismaleimide-diallyl bisphenol A copolymerization and preparation method thereof, fiber composite material and preparation method thereof 中国工程物理研究院化工材料研究所 2024-09-06 CN claimed
CN-118440237-A Self-repairing polymer, preparation method and application thereof, self-repairing coating, cable and communication equipment 武汉烽火锐拓科技有限公司 2024-08-06 CN claimed
CN-118126321-A Ultra-high heat-resistant and detachable recovery type thermosetting polymer based on self-polymerization of dithiobismaleimide and preparation method thereof 中国工程物理研究院化工材料研究所 2024-06-04 CN claimed
CN-117203225-A Artificial TRAP cage, use thereof and preparation method thereof 雅盖隆大学 2023-12-08 CN claimed
CN-116183923-A Panel for detecting APC/tumor immune co-stimulatory molecules 杭州奥明瑞康医学检验实验室有限公司 2023-05-30 CN claimed
CN-115997016-A Composition comprising nucleic acid nanoparticles having modular functional groups 西克斯福德生物科学有限公司 2023-04-21 CN claimed
CN-108026527-B Defined multiconjugated oligonucleotides MPEG LA有限责任公司 2022-05-10 CN claimed
US-11059938-B2 Film composition and a film prepared thereby INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2021-07-13 US claimed
EP-1446418-A4 INTEGRIN TARGETING COMPOUNDS SCRIPPS RESEARCH INST (US) 2006-05-17 EP claimed
JP-2005514430-A 2005-05-19 JP claimed
EP-1446418-A2 INTEGRIN TARGETING COMPOUNDS The Scripps Research Institute (US) 2004-08-18 EP claimed
EP-1443963-A2 ANTIBODY TARGETING COMPOUNDS The Scripps Research Institute (US) 2004-08-11 EP claimed
US-20030190676-A1 Antibody targeting compounds THE SCRIPPS RESEARCH INSTITUTE (US) 2003-10-09 US claimed
US-20030175921-A1 Antibody targeting compounds THE SCRIPPS RESEARCH INSTITUTE 2003-09-18 US claimed
WO-2003059251-A2 ANTIBODY TARGETING COMPOUNDS THE SCRIPPS RESEARCH INSTITUTE (US) 2003-07-24 WO claimed
US-20030129188-A1 Integrin targeting compounds THE SCRIPPS RESEARCH INSTITUTE 2003-07-10 US claimed
WO-2003034995-A2 INTEGRIN TARGETING COMPOUNDS THE SCRIPPS RESEARCH INSTITUTE (US) 2003-05-01 WO claimed
US-4004627-A Pneumatic tire with sidewall composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-01-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030175921-A1 Antibody targeting compounds CD47, CD22, FCGR2A MGLL 4286/4885GSK3A 1635/4885GSK3B 1702/4885
US-20030129188-A1 Integrin targeting compounds ITGAV, ITGB1, ITGB2 MGLL 4522/4885GSK3A 2214/4885GSK3B 2060/4885
US-20030190676-A1 Antibody targeting compounds CD47, CD22, FCGR2A MGLL 4286/4885GSK3A 1635/4885GSK3B 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.