Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572996 | 0.88 | TERT (0.55) | CYP1A1CYP1B1KDM1ACYP1A2ABCC1 | |
| SCHEMBL19354056 | 0.87 | PDE5A (0.61) | AKT1DYRK1ADYRK1BCYP1A1CYP1B1 | |
| SCHEMBL8431065 | 0.86 | DYRK1A (0.55) | AKT1DYRK1ADYRK1BCYP1B1PDE5A | |
| SCHEMBL8307616 | 0.85 | CYP1A1 (0.58) | AKT1DYRK1ADYRK1BCYP1A1CYP1B1 | |
| SCHEMBL8304148 | 0.84 | DYRK1A (0.49) | AKT1DYRK1ADYRK1BCYP1A1CYP1B1 | |
| SCHEMBL8305265 | 0.84 | CYP1B1 (0.65) | AKT1CYP1A1CYP1B1KDM1ACYP1A2 | |
| SCHEMBL8427304 | 0.84 | DYRK1A (0.52) | AKT1DYRK1ADYRK1BCYP1B1CYP1A2 | |
| SCHEMBL8304151 | 0.82 | PARP1 (0.56) | AKT1DYRK1ADYRK1BCYP1A1CYP1B1 | |
| SCHEMBL5163188 | 0.82 | TERT (0.70) | CYP1A1CYP1B1KDM1ACYP1A2ABCC1 | |
| SCHEMBL20045159 | 0.80 | DYRK1A (0.84) | AKT1DYRK1ADYRK1BCYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |