Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 3/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.58 |
| ▸ | BCL2 | P10415 | 1/20 | 0.57 |
| ▸ | TERT | O14746 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379704 | 0.91 | DYRK1A (0.64) | CYP1A1CYP1B1CYP1A2ABCC1BCL2 | |
| SCHEMBL8574988 | 0.86 | DYRK1A (0.50) | CYP1B1KDM1ABCL2TERTAKT1 | |
| SCHEMBL8308207 | 0.85 | AKT1 (0.61) | CYP1A1CYP1B1KDM1ACYP1A2ABCC1 | |
| SCHEMBL8305241 | 0.84 | KDM4E (0.52) | CYP1A1CYP1B1KDM1ACYP1A2BCL2 | |
| SCHEMBL8429610 | 0.84 | DYRK1A (0.48) | CYP1B1CYP1A2BCL2TERTAKT1 | |
| SCHEMBL5163188 | 0.83 | TERT (0.70) | CYP1A1CYP1B1KDM1ACYP1A2ABCC1 | |
| SCHEMBL8304917 | 0.83 | CYP1A1 (0.67) | CYP1A1CYP1B1KDM1ACYP1A2ABCC1 | |
| SCHEMBL8305238 | 0.81 | AKT1 (0.52) | BCL2AKT1DYRK1ADYRK1BPARP1 | |
| SCHEMBL3173373 | 0.81 | CYP1B1 (0.54) | CYP1A1CYP1B1CYP1A2HDAC6BCL2 | |
| SCHEMBL16894632 | 0.80 | ACHE (0.76) | CYP1A1CYP1B1KDM1ACYP1A2ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |