SCHEMBL20045159

SCHEMBL20045159

COc1cc(-c2cc(=O)c3c(O)cc(O)c(CC=C(C)C)c3o2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.84
DYRK1B Q9Y463 1/20 0.84
AKT1 P31749 2/20 0.78
PDE5A O76074 2/20 0.73
ESR1 P03372 1/20 0.73
PDE4D Q08499 1/20 0.73
ESR2 Q92731 1/20 0.73
SLC22A2 O15244 1/20 0.63
SLC22A1 O15245 1/20 0.63
PTGES O14684 1/20 0.62
ALOX5 P09917 1/20 0.62
KDM4E B2RXH2 2/20 0.59
USP2 O75604 1/20 0.59
CYP3A4 P08684 1/20 0.59
MEN1 O00255 2/20 0.57
ALDH1A1 P00352 2/20 0.57
POLB P06746 2/20 0.57
MAPT P10636 2/20 0.57
KMT2A Q03164 2/20 0.57
GAA P10253 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20045165 0.92 DYRK1A (1.00) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL20045166 0.91 DYRK1A (0.71) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL28950297 0.89 SLC22A2 (0.72) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL3192297 0.89 AKT1 (0.71) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL4828372 0.88 AKT1 (1.00) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL4227433 0.87 PDE5A (0.80) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL27013412 0.86 AKT1 (0.83) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL29808704 0.86 AKT1 (0.83) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL1231403 0.85 PDE4D (1.00) DYRK1ADYRK1BAKT1PDE5AESR1
SCHEMBL29808504 0.85 PDE4D (1.00) DYRK1ADYRK1BAKT1PDE5AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144901-A1 CUSTOMIZABLE LYOPHILIZED AGENT FOR IMAGE-GUIDED RADIOTHERAPY AND DRUG DELIVERY THE JOHNS HOPKINS UNIVERSITY (US) 2026-05-28 US claimed
US-20250381166-A1 Cannabis-Derived Flavonoids And Related Methods CANURTA INC (CA) 2025-12-18 US claimed
WO-2025137725-A2 A METHOD OF CULTIVATING, PREPARING, AND USING A MATRIX-BLANK BIOMASS PAULI CHRISTOPHER STEPHEN (US) 2025-06-26 WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20240050512-A1 REDUCTION OF VIRAL INFECTIONS PHOXBIO LIMITED (IE) 2024-02-15 US claimed
US-20240026314-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2024-01-25 US claimed
US-20240018114-A1 PREPARATION METHOD FOR CANNFLAVIN COMPOUNDS DEYI PHARMACEUTICAL LTD. (CN) 2024-01-18 US claimed
EP-4250991-A1 REDUCTION OF VIRAL INFECTIONS Phoxbio Limited (IE) 2023-10-04 EP claimed
EP-4251758-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS Rothstein, Steven (CA) 2023-10-04 EP claimed
EP-4223748-A1 PREPARATION METHOD FOR CANNFLAVIN COMPOUNDS Deyi Pharmaceutical Ltd. (CN) 2023-08-09 EP claimed
WO-2023141695-A1 CANNABIS-DERIVED FLAVONOIDS AND RELATED METHODS CANURTA INC. (CA) 2023-08-03 WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022109736-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2022-06-02 WO claimed
WO-2022112430-A1 REDUCTION OF VIRAL INFECTIONS PHOXBIO LIMITED (IE) 2022-06-02 WO claimed
US-20260144901-A1 CUSTOMIZABLE LYOPHILIZED AGENT FOR IMAGE-GUIDED RADIOTHERAPY AND DRUG DELIVERY THE JOHNS HOPKINS UNIVERSITY (US) 2026-05-28 US disclosed
US-20250381204-A1 A CANNABINOID MIXTURE WITH TERPENES FOR THE TREATMENT OF ANXIETY TTS PHARMA LTD (GB) 2025-12-18 US disclosed
US-20180098961-A1 THERAPEUTIC AGENTS CONTAINING CANNABIS FLAVONOID DERIVATIVES TARGETING KINASES, SIRTUINS AND ONCOGENIC AGENTS FOR THE TREATMENT OF CANCERS FLAVOCURE BIOTECH, INC. 2018-04-12 US disclosed
US-20180098961-A1 THERAPEUTIC AGENTS CONTAINING CANNABIS FLAVONOID DERIVATIVES TARGETING KINASES, SIRTUINS AND ONCOGENIC AGENTS FOR THE TREATMENT OF CANCERS FLAVOCURE BIOTECH, INC. 2018-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250381204-A1 A CANNABINOID MIXTURE WITH TERPENES FOR THE TREATMENT OF ANXIETY CNR1, CNR2, CTNND1 DYRK1A 1356/4885DYRK1B 1466/4885AKT1 1768/4885
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB DYRK1A 4736/4885DYRK1B 4723/4885AKT1 357/4885
US-20240018114-A1 PREPARATION METHOD FOR CANNFLAVIN COMPOUNDS HSPB1, HMBS, CYP8B1 DYRK1A 3443/4885DYRK1B 2112/4885AKT1 2743/4885
US-20240050512-A1 REDUCTION OF VIRAL INFECTIONS TFRC, ZFR, HAMP DYRK1A 4879/4885DYRK1B 4877/4885AKT1 3695/4885
US-20180098961-A1 THERAPEUTIC AGENTS CONTAINING CANNABIS FLAVONOID DERIVATIVES TARGETING KINASES, SIRTUINS AND ONCOGENIC AGENTS FOR THE TREATMENT OF CANCERS BRDT, BRD4, CKS2 DYRK1A 2472/4885DYRK1B 2251/4885AKT1 450/4885
US-20260144901-A1 CUSTOMIZABLE LYOPHILIZED AGENT FOR IMAGE-GUIDED RADIOTHERAPY AND DRUG DELIVERY GZMB, CTSZ, SLC39A11 DYRK1A 986/4885DYRK1B 538/4885AKT1 2635/4885
US-20240026314-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS COMT, PNMT, GNMT DYRK1A 4386/4885DYRK1B 4349/4885AKT1 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.