Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 11/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8364678 | 0.99 | HTR4 (0.43) | HTR4CYP2D6CYP2C9MEN1ALDH1A1 | |
| SCHEMBL6961633 | 0.84 | HTR4 (0.47) | HTR4CYP2D6CYP2C9MEN1ALDH1A1 | |
| Bromide SCHEMBL7744560 | 0.84 | HTR4 (0.46) | HTR4CYP2D6CYP2C9MEN1ALDH1A1 | |
| SCHEMBL8306432 | 0.77 | HTR4 (0.53) | HTR4CYP2D6CYP2C9HTR3AHTR2C | |
| SCHEMBL8305104 | 0.77 | HTR4 (0.44) | HTR4 | |
| SCHEMBL8309549 | 0.77 | ACHE (0.51) | HTR4ACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL8364693 | 0.77 | HTR4 (0.52) | HTR4CYP2D6CYP2C9HTR3AHTR2C | |
| SCHEMBL8309535 | 0.76 | DRD4 (0.44) | HTR4CYP2D6CYP2C9ACHEHTR3A | |
| Hydrochloric Acid SCHEMBL8368070 | 0.76 | HTR4 (0.43) | HTR4 | |
| SCHEMBL8304880 | 0.71 | HTR4 (0.44) | HTR4ACHEHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |