Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 3/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305542 | 0.91 | DDR1 (0.32) | ALDH1A1SMN1; SMN2PPARGMAPTHSD17B13 | |
| SCHEMBL8309156 | 0.90 | DDR1 (0.32) | ALDH1A1SMN1; SMN2PPARGMAPTHSD17B13 | |
| SCHEMBL8304561 | 0.88 | P2RX3 (0.36) | ALDH1A1SMN1; SMN2MAPTDDR1P2RX3 | |
| SCHEMBL8308815 | 0.86 | — | — | |
| SCHEMBL8303240 | 0.81 | RORC (0.37) | ALDH1A1KDM4EPPARGMAPTHSD17B13 | |
| SCHEMBL8307160 | 0.78 | KDM4E (0.37) | ALDH1A1KDM4EDDR1 | |
| SCHEMBL7472616 | 0.75 | P2RX3 (0.34) | ALDH1A1SMN1; SMN2KDM4EGAAPPARG | |
| SCHEMBL10614819 | 0.70 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL8308410 | 0.68 | — | — | |
| SCHEMBL7471410 | 0.66 | PPARG (0.33) | ALDH1A1SMN1; SMN2PPARGHSD17B13CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |