Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 15/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303240 | 0.89 | RORC (0.37) | KDM4EMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL8303099 | 0.89 | HSD17B13 (0.33) | KDM4EALDH1A1DDR1 | |
| SCHEMBL8304561 | 0.80 | P2RX3 (0.36) | ALDH1A1DDR1 | |
| SCHEMBL8308409 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1DDR1 | |
| SCHEMBL8309156 | 0.76 | DDR1 (0.32) | ALDH1A1DDR1 | |
| SCHEMBL7476618 | 0.75 | ACLY (0.37) | KDM4EMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL7471937 | 0.63 | BCAT1 (0.40) | KDM4EALDH1A1KMT2ADDR1 | |
| SCHEMBL7472788 | 0.62 | RORC (0.42) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL7476563 | 0.62 | LMNA (0.36) | MEN1ALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL16741050 | 0.62 | PSEN1 (0.41) | KDM4EMEN1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |