Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 14/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308409 | 0.91 | ALDH1A1 (0.35) | DDR1PPARGHSD17B13ALDH1A1MAPT | |
| SCHEMBL8304561 | 0.90 | P2RX3 (0.36) | DDR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8309156 | 0.88 | DDR1 (0.32) | DDR1PPARGHSD17B13ALDH1A1MAPT | |
| SCHEMBL8303099 | 0.84 | HSD17B13 (0.33) | DDR1HSD17B13ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8308815 | 0.83 | — | — | |
| SCHEMBL8303240 | 0.82 | RORC (0.37) | PPARGHSD17B13ALDH1A1MAPTHPGD | |
| SCHEMBL8307160 | 0.79 | KDM4E (0.37) | DDR1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8305445 | 0.79 | DDR1 (0.36) | DDR1HPGDTSHRHSD17B10 | |
| SCHEMBL7468861 | 0.74 | PPARG (0.35) | PPARGHPGDCMA1 | |
| SCHEMBL7471937 | 0.72 | BCAT1 (0.40) | DDR1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |