Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | FPR2 | P25090 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362837 | 0.82 | FPR2 (0.52) | CTSLFPR2CTSBL3MBTL1MMP8 | |
| SCHEMBL8310281 | 0.82 | CYP3A4 (0.50) | CTSSPOLBGAAKMT2AALDH1A1 | |
| SCHEMBL9087713 | 0.82 | CAPN1 (0.52) | CTSLFPR2CTSBL3MBTL1MMP8 | |
| SCHEMBL9087720 | 0.76 | ITGB1 (0.49) | CTSLFPR2CTSBMMP8MMP1 | |
| SCHEMBL9087719 | 0.75 | ITGA4 (0.50) | FPR2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7268468 | 0.74 | POLB (0.76) | CTSLCTSBCTSSATML3MBTL1 | |
| SCHEMBL7268474 | 0.74 | POLB (0.76) | CTSLCTSBCTSSATML3MBTL1 | |
| SCHEMBL16254296 | 0.74 | MMP8 (0.62) | CTSLCTSSMMP8MMP1MMP3 | |
| SCHEMBL20176845 | 0.74 | MMP8 (0.62) | CTSLCTSSMMP8MMP1MMP3 | |
| SCHEMBL7354191 | 0.73 | FPR2 (0.54) | FPR2ATML3MBTL1MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |