Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354191 | 0.91 | FPR2 (0.54) | FPR2MMP1MMP3MEN1KMT2A | |
| SCHEMBL9087713 | 0.87 | CAPN1 (0.52) | FPR2MMP1MMP3MEN1KMT2A | |
| SCHEMBL7354780 | 0.84 | LMNA (0.49) | FPR2KMT2AALDH1A1MMP8L3MBTL1 | |
| SCHEMBL8308565 | 0.82 | CTSL (0.51) | FPR2MMP1MMP3KMT2AALDH1A1 | |
| SCHEMBL7357371 | 0.81 | CYP3A4 (0.49) | MEN1KMT2AALDH1A1CTSLCTSB | |
| SCHEMBL7361795 | 0.80 | L3MBTL1 (0.51) | FPR2MEN1KMT2AALDH1A1P2RY12 | |
| SCHEMBL9087719 | 0.80 | ITGA4 (0.50) | FPR2ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7359406 | 0.79 | MMP1 (0.49) | MMP1MMP8L3MBTL1 | |
| SCHEMBL7356396 | 0.79 | CAPN1 (0.53) | FPR2MMP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7360469 | 0.79 | L3MBTL1 (0.44) | FPR2ALDH1A1MMP8CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |