Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.49 |
| ▸ | HTR1A | P08908 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 8/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310251 | 0.97 | DRD2 (0.46) | DRD2HTR1AHTR2ADRD1DRD4 | |
| SCHEMBL6584872 | 0.97 | DRD2 (0.48) | DRD2HTR1AHTR2AMAOAMAOB | |
| SCHEMBL6586928 | 0.95 | MAOA (0.45) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL6585890 | 0.84 | DRD2 (0.43) | DRD2HTR1AHTR2AMAOAMAOB | |
| SCHEMBL6586944 | 0.83 | MAOA (0.58) | DRD2HTR1AHTR2ADRD4HTR2C | |
| SCHEMBL6587330 | 0.83 | DRD2 (0.43) | DRD2HTR1AHTR2AMAOAMAOB | |
| SCHEMBL6584969 | 0.83 | MAOA (0.67) | DRD2MAOAMAOB | |
| SCHEMBL6585295 | 0.83 | MAOA (0.59) | DRD2HTR1AHTR2ADRD4HTR2C | |
| SCHEMBL6585490 | 0.82 | MAOA (0.68) | DRD2MAOAMAOB | |
| SCHEMBL6584734 | 0.82 | HTR1A (0.41) | DRD2HTR1AHTR2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |