Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307759 | 0.77 | LMNA (0.35) | LMNA | |
| SCHEMBL8311142 | 0.77 | PRKCA (0.39) | — | |
| SCHEMBL7830363 | 0.70 | MIF (0.32) | LMNA | |
| SCHEMBL9183340 | 0.70 | MIF (0.32) | LMNA | |
| Chloroform SCHEMBL8309854 | 0.69 | — | — | |
| SCHEMBL4002605 | 0.69 | LMNA (0.43) | LMNA | |
| SCHEMBL9692302 | 0.68 | — | — | |
| SCHEMBL19700361 | 0.67 | MIF (0.33) | LMNA | |
| Chloroform SCHEMBL8307756 | 0.67 | ALDH1A1 (0.34) | LMNA | |
| SCHEMBL6898384 | 0.66 | MMP1 (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914339-A | ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0901484-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043273-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |