Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312126 | 0.83 | HPD (0.34) | L3MBTL1 | |
| SCHEMBL8310774 | 0.82 | MEN1 (0.30) | MAPK1MEN1KMT2AHPGDTSHR | |
| SCHEMBL8310429 | 0.76 | LMNA (0.42) | SMN1; SMN2LMNAMAPK1PDE4DMAPT | |
| SCHEMBL8310362 | 0.74 | DPP4 (0.42) | SMN1; SMN2LMNAMAPTTDP1MEN1 | |
| SCHEMBL8488170 | 0.72 | — | — | |
| SCHEMBL8309821 | 0.71 | MEN1 (0.33) | SMN1; SMN2LMNAMAPK1MAPTMEN1 | |
| SCHEMBL9303460 | 0.70 | SCN5A (0.35) | MAPTMEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL7332384 | 0.67 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAMAPK1MAPTMEN1 | |
| SCHEMBL8309433 | 0.67 | — | — | |
| SCHEMBL7437362 | 0.66 | LMNA (0.55) | SMN1; SMN2LMNAMAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |