Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312122 | 0.84 | HPD (0.36) | TDP1NPC1KDM4EHDAC3HDAC4 | |
| SCHEMBL8310772 | 0.83 | CES2 (0.33) | — | |
| SCHEMBL8310430 | 0.76 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL8309818 | 0.72 | LMNA (0.39) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL8310362 | 0.72 | DPP4 (0.42) | LMNASMN1; SMN2MAPTTDP1MEN1 | |
| SCHEMBL9303456 | 0.71 | ADORA3 (0.35) | LMNASMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL8488169 | 0.69 | CES2 (0.34) | MEN1KMT2A | |
| SCHEMBL7437362 | 0.67 | LMNA (0.55) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL29176411 | 0.67 | CTSD (0.54) | LMNASMN1; SMN2MAPK1MAPTMEN1 | |
| SCHEMBL10740410 | 0.66 | LMNA (0.56) | LMNASMN1; SMN2MAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |