Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 7/20 | 0.35 |
| ▸ | DRD4 | P21917 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159466 | 0.79 | KDM4E (0.54) | L3MBTL1HSD17B10DRD2DRD4KDM4E | |
| SCHEMBL2078054 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4ELMNAHTR1A | |
| SCHEMBL8784661 | 0.68 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1HSD17B10ALOX15IDO1 | |
| SCHEMBL83700 | 0.68 | PDK4 (0.68) | HTR6 | |
| SCHEMBL5189044 | 0.67 | PTGS2 (0.47) | ALDH1A1L3MBTL1HSD17B10IDO1 | |
| SCHEMBL23536396 | 0.67 | ALDH1A1 (0.39) | ALDH1A1DRD2DRD4KDM4ELMNA | |
| SCHEMBL4850917 | 0.66 | PTGS2 (0.46) | ALDH1A1L3MBTL1HSD17B10IDO1 | |
| SCHEMBL4856447 | 0.66 | PTGS2 (0.46) | ALDH1A1L3MBTL1HSD17B10IDO1 | |
| SCHEMBL4850921 | 0.66 | PTGS2 (0.46) | ALDH1A1L3MBTL1HSD17B10IDO1 | |
| Hydrochloric Acid SCHEMBL21465353 | 0.65 | ALDH1A1 (0.93) | ALDH1A1L3MBTL1HSD17B10KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120270885-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270885-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042938-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-20090042938-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270885-A1 | CHEMICAL COMPOUNDS | H1-0, CHRM1, MRM1 | ALDH1A1 927/4885L3MBTL1 460/4885HSD17B10 4553/4885 |
| US-20090042938-A1 | Chemical Compounds | CHRM1, MRM1, H1-0 | ALDH1A1 831/4885L3MBTL1 417/4885HSD17B10 4611/4885 |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | ACHE, CHRM1, CHRM2 | ALDH1A1 409/4885L3MBTL1 194/4885HSD17B10 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.