Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311946 | 0.87 | KDM4E (0.61) | LMNATHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL8308066 | 0.78 | LMNA (0.86) | LMNATHRBKMT2ARXFP1MAPT | |
| SCHEMBL8303840 | 0.73 | KMT2A (0.80) | LMNATHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL8304067 | 0.73 | LMNA (0.78) | LMNATHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL8308627 | 0.72 | KMT2A (0.73) | LMNATHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL8311182 | 0.71 | RXFP1 (0.61) | LMNATHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL13253390 | 0.71 | ATM (0.54) | LMNAKMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL8308067 | 0.71 | KMT2A (0.78) | LMNATHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL8308248 | 0.70 | RXFP1 (0.75) | LMNATHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL8311184 | 0.70 | RXFP1 (0.60) | LMNATHRBKMT2ARXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |