SCHEMBL831155

SCHEMBL831155

O=[C]CCCCCC(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9259981 1.00 ALOX15 (0.30) ALOX15
SCHEMBL835617 0.97
SCHEMBL693530 0.89
SCHEMBL19554084 0.80
SCHEMBL605855 0.77
SCHEMBL2155057 0.76
SCHEMBL1676791 0.76
SCHEMBL2153675 0.76
SCHEMBL2154219 0.76
SCHEMBL4652997 0.76 ALOX15 (0.33) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230097871-A1 UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR TAISHO PHARMACEUTICAL CO., LTD. (JP) 2023-03-30 US disclosed
EP-4008405-A1 UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR Taisho Pharmaceutical Co., Ltd. (JP) 2022-06-08 EP disclosed
CN-114206832-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2022-03-18 CN disclosed
US-10172854-B2 Compositions and methods for treating mitochondrial diseases BIOVISTA, INC. (US) 2019-01-08 US disclosed
US-20180110775-A1 COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL DISEASES BIOVISTA INC (US) 2018-04-26 US disclosed
US-9763939-B2 Compositions and methods for treating mitochondrial diseases BIOVISTA, INC. (US) 2017-09-19 US disclosed
US-20160213667-A1 COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL DISEASES BIOVISTA INC (US) 2016-07-28 US disclosed
EP-2375900-B1 METHODS FOR TREATING MULTIPLE SCLEROSIS USING TETRACYCLIC PYRAZINOINDOLES BIOVISTA INC (US) 2016-03-02 EP disclosed
WO-2013130422-A1 COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL DISEASES BIOVISTA, INC. (US) 2013-09-06 WO disclosed
US-8497397-B2 Substituted acrylamide derivative and pharmaceutical composition comprising the same DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-07-30 US disclosed
EP-2375900-A1 METHODS FOR TREATING MULTIPLE SCLEROSIS USING TETRACYCLIC PYRAZINOINDOLES Biovista, Inc. (US) 2011-10-19 EP disclosed
WO-2010068867-A1 METHODS FOR TREATING MULTIPLE SCLEROSIS USING TETRACYCLIC PYRAZINOINDOLES BIOVISTA, INC. (US) 2010-06-17 WO disclosed
US-20090292024-A1 SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-11-26 US disclosed
US-20090118199-A1 SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAIICHI SANKYO COMPANY , LIMITED (JP) 2009-05-07 US disclosed
EP-1908466-A1 SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Daiichi Sankyo Company, Limited (JP) 2008-04-09 EP disclosed
EP-1880720-A1 SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Daiichi Sankyo Company, Limited (JP) 2008-01-23 EP disclosed
US-20060041144-A1 Phenylpyridine compound and fungicidal compostion containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-23 US disclosed
US-20050192359-A1 N-biphenylamides and fungicidal compositions containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-09-01 US disclosed
EP-1541557-A1 PHENYLPYRIDINE COMPOUND AND BACTERICIDAL COMPOSITION CONTAINING THE SAME Sumitomo Chemical Company, Limited (JP) 2005-06-15 EP disclosed
EP-1486483-A1 N-BIPHENYLAMIDES AND FUNGICIDAL COMPOSITIONS CONTAINING THE SAME Sumitomo Chemical Company, Limited (JP) 2004-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090292024-A1 SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME PTMS, C1S, ACP3 ALOX15 3105/4885
US-20230097871-A1 UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR LPAR1, LPAR2, LPAR3 ALOX15 638/4885
US-20090118199-A1 SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ACR, NAT1, C1S ALOX15 2002/4885
US-20050192359-A1 N-biphenylamides and fungicidal compositions containing the same CBR3, ARNT, CBR1 ALOX15 2773/4885
US-10172854-B2 Compositions and methods for treating mitochondrial diseases MT-ND2, CS, UQCRC2 ALOX15 1045/4885
US-20180110775-A1 COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL DISEASES MT-ND2, CS, UQCRC2 ALOX15 1045/4885
US-20060041144-A1 Phenylpyridine compound and fungicidal compostion containing the same CBR3, CYP1A1, PAH ALOX15 3228/4885
US-20160213667-A1 COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL DISEASES MT-ND2, CS, UQCRC2 ALOX15 1045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.