Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414489 | 0.82 | SIGMAR1 (0.46) | APPSIGMAR1HRH3ALDH1A1RAB9A | |
| SCHEMBL8308762 | 0.81 | IDO1 (0.44) | HSD17B10APPSIGMAR1HRH3IDO1 | |
| SCHEMBL12992270 | 0.78 | SIGMAR1 (0.45) | APPSIGMAR1HRH3 | |
| SCHEMBL9414462 | 0.78 | SIGMAR1 (0.45) | APPSIGMAR1HRH3 | |
| SCHEMBL24220107 | 0.77 | SMN1; SMN2 (0.52) | HSD17B10SMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL7833142 | 0.77 | KMT2A (0.55) | SMN1; SMN2APPALDH1A1IDO1NPC1 | |
| SCHEMBL8307284 | 0.75 | TDP1 (0.50) | SMN1; SMN2APPCRBNSIGMAR1ALDH1A1 | |
| SCHEMBL8310493 | 0.74 | MAOB (0.39) | APPSIGMAR1HRH3ALDH1A1IDO1 | |
| SCHEMBL8063627 | 0.72 | KMT2A (0.61) | SMN1; SMN2HRH3ALDH1A1NPC1RAB9A | |
| SCHEMBL9479861 | 0.72 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |