Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414489 | 0.79 | SIGMAR1 (0.46) | MAPTALDH1A1RAB9AGAAL3MBTL1 | |
| SCHEMBL9479861 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2MAPTALDH1A1LMNAEPHX2 | |
| SCHEMBL9414488 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2MAPTALDH1A1LMNAEPHX2 | |
| SCHEMBL8308762 | 0.78 | IDO1 (0.44) | TSHRKMT2AHPGDHSD17B10 | |
| SCHEMBL8311656 | 0.77 | HSD17B10 (0.39) | SMN1; SMN2ALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL9414462 | 0.75 | SIGMAR1 (0.45) | MAPT | |
| SCHEMBL12992270 | 0.75 | SIGMAR1 (0.45) | MAPT | |
| SCHEMBL8063627 | 0.75 | KMT2A (0.61) | SMN1; SMN2ALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL7833142 | 0.74 | KMT2A (0.55) | SMN1; SMN2ALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL8307284 | 0.72 | TDP1 (0.50) | SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | TICURE LTD. (IL) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | FABP4, FABP2, FABP1 | SMN1; SMN2 3294/4885MAPT 1884/4885ALDH1A1 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.