Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894019 | 0.80 | GSK3B (0.42) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL16922196 | 0.80 | GSK3B (0.42) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL29700721 | 0.70 | ACHE (0.43) | — | |
| SCHEMBL1201428 | 0.69 | NPC1 (0.60) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL16922186 | 0.68 | KMT2A (0.63) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL4883159 | 0.68 | KMT2A (0.63) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL5954011 | 0.67 | ALDH1A1 (0.48) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL2233657 | 0.67 | ALDH1A1 (0.59) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL13211865 | 0.67 | MMP13 (0.46) | ALDH1A1HTTLMNACES2CES1 | |
| SCHEMBL9850638 | 0.67 | CHRM2 (0.51) | ALDH1A1HTTLMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005010002-A1 | PROCESS FOR THE SYNTHESIS OF ZOLPIDEM | RANBAXY LABORATORIES LIMITED (IN) | 2005-02-03 | — | — | WO | disclosed |