Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.51 |
| ▸ | WNT3A | P56704 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922186 | 1.00 | KMT2A (0.63) | KMT2AGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL16552778 | 0.85 | KMT2A (0.83) | KMT2AGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL15223664 | 0.84 | KMT2A (0.58) | KMT2AGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL3966037 | 0.83 | NPC1 (0.60) | KMT2ACTNNB1MEN1NPC1RAB9A | |
| SCHEMBL940512 | 0.82 | KMT2A (0.63) | KMT2AGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL1201428 | 0.82 | NPC1 (0.60) | KMT2AGSK3BMEN1NPC1RAB9A | |
| SCHEMBL1258744 | 0.81 | KMT2A (0.59) | KMT2AGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL30552473 | 0.80 | MMP1 (0.61) | KMT2AGSK3BMEN1NPC1RAB9A | |
| SCHEMBL5458640 | 0.78 | GSR (0.64) | KMT2AGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL822848 | 0.78 | KMT2A (0.70) | KMT2AGSK3BCTNNB1WNT3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054669-A1 | Process for the synthesis of zolpidem | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | US | claimed |
| CN-114105974-A | Preparation method of zolpidem | 鲁南制药集团股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114057729-A | Preparation method of zolpidem | 鲁南制药集团股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-20080262025-A1 | Processes for the Preparation of Zolpidem and its Hemitartrate | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-23 | — | — | US | disclosed |
| US-20080262025-A1 | Processes for the Preparation of Zolpidem and its Hemitartrate | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-23 | — | — | US | disclosed |
| US-20080262025-A1 | Processes for the Preparation of Zolpidem and its Hemitartrate | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-23 | — | — | US | disclosed |
| EP-1395586-B1 | METHOD FOR THE PRODUCTION OF ZOLPIDEM | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-02-14 | — | — | EP | disclosed |
| EP-1660496-A1 | PROCESS FOR THE SYNTHESIS OF ZOLPIDEM | Ranbaxy Laboratories Limited (IN) | 2006-05-31 | — | — | EP | disclosed |
| WO-2006008636-A2 | PROCESSES FOR THE PREPARATION OF ZOLPIDEM AND ITS HEMITARTRATE | RANBAXY LABORATORIES LIMITED (IN) | 2006-01-26 | — | — | WO | disclosed |
| US-6921839-B2 | Synthesis of N,N-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-26 | — | — | US | disclosed |
| US-6921839-B2 | Synthesis of N,N-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-26 | — | — | US | disclosed |
| US-20050054669-A1 | Process for the synthesis of zolpidem | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | US | disclosed |
| US-20050054669-A1 | Process for the synthesis of zolpidem | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | US | disclosed |
| WO-2005010002-A1 | PROCESS FOR THE SYNTHESIS OF ZOLPIDEM | RANBAXY LABORATORIES LIMITED (IN) | 2005-02-03 | — | — | WO | disclosed |
| WO-2005010002-A1 | PROCESS FOR THE SYNTHESIS OF ZOLPIDEM | RANBAXY LABORATORIES LIMITED (IN) | 2005-02-03 | — | — | WO | disclosed |
| EP-1370515-A2 | SYNTHESIS OF N,N-DIMETHYL-3-(4-METHYL) BENZOYL PROPIONAMIDE, A KEY INTERMEDIATE OF ZOLPIDEM | RANBAXY LABORATORIES, LTD. (IN) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002018303-A3 | SYNTHESIS OF N,N-DIMETHYL-3-(4-METHYL) BENZOYL PROPIONAMIDE, A KEY INTERMEDIATE OF ZOLPIDEM | RANBAXY LAB LTD (IN) | 2003-10-02 | — | — | WO | disclosed |
| WO-2002018303-A2 | SYNTHESIS OF N,N-DIMETHYL-3-(4-METHYL) BENZOYL PROPIONAMIDE, A KEY INTERMEDIATE OF ZOLPIDEM | RANBAXY LABORATORIES LIMITED (IN) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054669-A1 | Process for the synthesis of zolpidem | TET2, KDM5B, HNMT | KMT2A 57/4885GSK3B 3343/4885CTNNB1 3993/4885 |
| US-20080262025-A1 | Processes for the Preparation of Zolpidem and its Hemitartrate | HTR5A, GABRA5, HTR4 | KMT2A 141/4885GSK3B 684/4885CTNNB1 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.