SCHEMBL4894019

SCHEMBL4894019

Cc1ccc(C(=O)C(Br)CC(=O)N(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.42
ALDH1A1 P00352 7/20 0.39
LMNA P02545 3/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
CHRM2 P08172 1/20 0.38
ADRA2B P18089 1/20 0.38
DRD3 P35462 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
HTT P42858 4/20 0.38
SLC6A3 Q01959 5/20 0.37
SLC6A2 P23975 4/20 0.37
SLC6A4 P31645 3/20 0.37
KMT2A Q03164 3/20 0.36
PKM P14618 2/20 0.36
ATM Q13315 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16922196 1.00 GSK3B (0.42) GSK3BALDH1A1LMNACES2CES1
SCHEMBL28761849 0.87 HDAC3 (0.41) GSK3BALDH1A1LMNACES2CES1
SCHEMBL1259362 0.84 GSK3B (0.40) GSK3BALDH1A1LMNACES2CES1
SCHEMBL12602855 0.81 GSK3B (0.46) GSK3BALDH1A1LMNACES2CES1
SCHEMBL19328352 0.81 KMT2A (0.47) GSK3BALDH1A1LMNACES2CES1
SCHEMBL8311841 0.80 ALDH1A1 (0.40) GSK3BALDH1A1LMNACES2CES1
SCHEMBL3110619 0.77 GSK3B (0.48) GSK3BALDH1A1LMNACES2CES1
SCHEMBL12593806 0.77 TDP1 (0.47) GSK3BALDH1A1LMNACES2CES1
SCHEMBL4937398 0.74 SLC6A3 (0.54) GSK3BALDH1A1LMNACES2CES1
SCHEMBL4938257 0.74 SLC6A3 (0.54) GSK3BALDH1A1LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080262025-A1 Processes for the Preparation of Zolpidem and its Hemitartrate RANBAXY LABORATORIES LIMITED (IN) 2008-10-23 US disclosed
US-20080262025-A1 Processes for the Preparation of Zolpidem and its Hemitartrate RANBAXY LABORATORIES LIMITED (IN) 2008-10-23 US disclosed
US-20080262025-A1 Processes for the Preparation of Zolpidem and its Hemitartrate RANBAXY LABORATORIES LIMITED (IN) 2008-10-23 US disclosed
US-20080262025-A1 Processes for the Preparation of Zolpidem and its Hemitartrate RANBAXY LABORATORIES LIMITED (IN) 2008-10-23 US disclosed
WO-2006008636-A3 PROCESSES FOR THE PREPARATION OF ZOLPIDEM AND ITS HEMITARTRATE RANBAXY LAB LTD (IN) 2006-08-17 WO disclosed
WO-2006008636-A2 PROCESSES FOR THE PREPARATION OF ZOLPIDEM AND ITS HEMITARTRATE RANBAXY LABORATORIES LIMITED (IN) 2006-01-26 WO disclosed
WO-2006008636-A2 PROCESSES FOR THE PREPARATION OF ZOLPIDEM AND ITS HEMITARTRATE RANBAXY LABORATORIES LIMITED (IN) 2006-01-26 WO disclosed
WO-2005010002-A1 PROCESS FOR THE SYNTHESIS OF ZOLPIDEM RANBAXY LABORATORIES LIMITED (IN) 2005-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262025-A1 Processes for the Preparation of Zolpidem and its Hemitartrate HTR5A, GABRA5, HTR4 GSK3B 684/4885ALDH1A1 2589/4885LMNA 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.