Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19520848 | 0.84 | MEN1 (0.73) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1901465 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL14511477 | 0.78 | MCL1 (0.49) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL14537227 | 0.77 | EIF4A1 (0.53) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL117405 | 0.74 | EPRS1 (0.71) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL26074025 | 0.74 | DHODH (0.60) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL13919572 | 0.73 | EIF4A1 (0.44) | KDM4EALDH1A1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL8327199 | 0.72 | KDM4E (0.74) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8324531 | 0.72 | MEN1 (0.77) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1441639 | 0.72 | ALDH1A1 (0.63) | MEN1KMT2AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |