SCHEMBL8554380

SCHEMBL8554380

Nc1c(F)cc(Cl)c2nc(C=C[C]=O)sc12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9148367 0.75 SMN1; SMN2 (0.38) SMN1; SMN2
SCHEMBL8312415 0.73 SMN1; SMN2 (0.37) SMN1; SMN2
Hydrochloric Acid SCHEMBL9147162 0.73 SMN1; SMN2 (0.37) SMN1; SMN2
SCHEMBL8334566 0.72 TLR8 (0.36) SMN1; SMN2
SCHEMBL8331898 0.69 KDR (0.36) SMN1; SMN2
SCHEMBL8310400 0.69 MAPT (0.36) SMN1; SMN2
SCHEMBL8329490 0.69 TLR8 (0.40) SMN1; SMN2
SCHEMBL8333788 0.67 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL8312356 0.66 ALDH1A1 (0.58) SMN1; SMN2
SCHEMBL8312265 0.63 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0862569-A1 SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION BASF AKTIENGESELLSCHAFT (DE) 1998-09-09 EP disclosed
WO-1997008171-A1 SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION BASF AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed