Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | AOC2 | O75106 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581041 | 0.82 | GAA (0.53) | GAAALOX15MAOBAOC2MAOA | |
| SCHEMBL1581040 | 0.82 | GAA (0.53) | GAAALOX15MAOBAOC2MAOA | |
| Hydrochloric Acid SCHEMBL836698 | 0.80 | GAA (0.51) | GAAALOX15MAOBAOC2MAOA | |
| SCHEMBL1221676 | 0.72 | WDR5 (0.64) | ALOX15MAOBAOC2MAOAAOC3 | |
| SCHEMBL12696331 | 0.72 | ALOX15 (0.56) | GAAALOX15MAOBAOC2MAOA | |
| SCHEMBL159433 | 0.72 | ALOX15 (0.56) | GAAALOX15MAOBAOC2MAOA | |
| SCHEMBL138162 | 0.72 | ALOX15 (0.68) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL19305271 | 0.72 | ALOX15 (0.60) | GAAALOX15LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL97376 | 0.72 | ALOX15 (0.60) | ALOX15MAOBAOC2MAOAAOC3 | |
| SCHEMBL27386501 | 0.72 | ALOX15 (0.60) | ALOX15MAOBAOC2MAOAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056823-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |