Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716298 | 0.90 | MCOLN3 (0.54) | MCOLN3TSHRMEN1KMT2AMAPT | |
| SCHEMBL8313913 | 0.82 | LMNA (0.49) | MEN1KMT2AMAPTAGTR1MAPK1 | |
| SCHEMBL4713378 | 0.80 | TDP1 (0.47) | MCOLN3TSHRMEN1KMT2APOLB | |
| SCHEMBL4716188 | 0.79 | AGTR1 (0.53) | TSHRMEN1KMT2AMAPTAGTR1 | |
| SCHEMBL4712690 | 0.78 | LMNA (0.57) | MCOLN3TSHRMEN1KMT2AMAPT | |
| SCHEMBL4716672 | 0.78 | CNR1 (0.44) | KMT2AMAPTAGTR1L3MBTL1POLB | |
| SCHEMBL4714628 | 0.78 | AGTR1 (0.52) | TSHRMEN1KMT2AMAPTAGTR1 | |
| SCHEMBL4716103 | 0.76 | MEN1 (0.51) | TSHRMEN1KMT2AMAPTAGTR1 | |
| SCHEMBL4716372 | 0.75 | AGTR1 (0.52) | MEN1KMT2AMAPTAGTR1L3MBTL1 | |
| SCHEMBL4716022 | 0.75 | ALDH1A1 (0.55) | MCOLN3TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092135-A2 | SUBSTITUTED BENZOSULPHONAMIDE AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA (SE) | 2004-10-28 | — | — | WO | disclosed |