Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.55 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314577 | 0.84 | SIGMAR1 (0.40) | CHRM1CHRM3HTR2CHTR7CHRM2 | |
| SCHEMBL8314770 | 0.75 | CHRM1 (0.40) | CHRM1CHRM3HTR7 | |
| SCHEMBL8314716 | 0.75 | HTR7 (0.48) | HTR2CHTR7HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL10600743 | 0.74 | HTR7 (0.47) | HTR2CHTR7HTR2AHTR2B | |
| SCHEMBL27580829 | 0.73 | CYP1A2 (0.51) | HTR2CHTR7HTR2AHTR2BCHRM5 | |
| SCHEMBL12751389 | 0.73 | DYRK2 (0.51) | HTR2CHTR7HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL6293547 | 0.72 | CYP1A2 (0.50) | HTR2CHTR7HTR2AHTR2BCHRM5 | |
| SCHEMBL8316812 | 0.72 | NISCH (0.40) | HTR2CHTR7HTR2A | |
| Hydrochloric Acid SCHEMBL7983894 | 0.72 | DYRK2 (0.50) | HTR2CHTR7HTR2AHTR2B | |
| SCHEMBL7934636 | 0.72 | CHRM1 (0.48) | CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |