Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314716 | 0.84 | HTR7 (0.48) | HTR2CHTR2AHTR2BHTR7HTR6 | |
| SCHEMBL8313295 | 0.84 | CHRM1 (0.55) | HTR2CHTR2AHTR2BHTR7CHRM1 | |
| Hydrochloric Acid SCHEMBL10600743 | 0.83 | HTR7 (0.47) | HTR2CHTR2AHTR2BHTR7HTR6 | |
| SCHEMBL1497170 | 0.81 | CYP26A1 (0.39) | PTGS2PTGS1CYP1A2 | |
| SCHEMBL8316750 | 0.81 | HTR1A (0.51) | HTR2CHTR2AHTR2BHTR7HTR1A | |
| SCHEMBL12751389 | 0.76 | DYRK2 (0.51) | HTR2CHTR2AHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL7983894 | 0.75 | DYRK2 (0.50) | HTR2CHTR2AHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL10601953 | 0.73 | HTR7 (0.42) | HTR2CHTR2AHTR2BHTR7HTR6 | |
| SCHEMBL8316880 | 0.73 | HRH3 (0.39) | SIGMAR1HTR2CHTR2AHTR2BHTR7 | |
| SCHEMBL16322736 | 0.72 | HTR2C (0.48) | SIGMAR1HTR2CHTR2AHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |