Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | HTR2C | P28335 | 9/20 | 0.37 |
| ▸ | HTR2B | P41595 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10600743 | 0.98 | HTR7 (0.47) | HTR7HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL8314577 | 0.84 | SIGMAR1 (0.40) | HTR7HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL8316750 | 0.81 | HTR1A (0.51) | HTR7HTR2CHTR2BHTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL10601953 | 0.79 | HTR7 (0.42) | HTR7HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL12751291 | 0.76 | IKBKB (0.51) | HTR7HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL6979971 | 0.75 | IKBKB (0.50) | HTR7HTR2CHTR2BHTR2A | |
| SCHEMBL8313295 | 0.75 | CHRM1 (0.55) | HTR7HTR2CHTR2BHTR2A | |
| SCHEMBL8315728 | 0.74 | PRCP (0.42) | HTR7HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL20015685 | 0.72 | IKBKB (0.48) | HTR7HTR2CHTR2BHTR2AHTR1A | |
| SCHEMBL8316812 | 0.72 | NISCH (0.40) | HTR7HTR2CHTR2AHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |
| EP-0401707-A1 | Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |